null

SMILES CN1CC(C1)C(=O)N[C@@H](CCCCCC(=O)c1ccon1)c1ncc([nH]1)-c1ccccc1F

InChI Key InChIKey=YNOXQYPNBSQQEI-FQEVSTJZSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50544211   

TargetHistone deacetylase 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50544211(CHEMBL4641682)copy SMILEScopy InChI
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of full length human recombinant FLAG-tagged HDAC1 expressed in HEK293F cells using FLUOR DE LYS as substrate preincubated for 3 hrs follo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0S85PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50544211(CHEMBL4641682)copy SMILEScopy InChI
Affinity DataIC50: 0.470nMAssay Description:Inhibition of full length human recombinant FLAG-tagged HDAC2 expressed in baculovirus infected Sf9 cells using FLUOR DE LYS as substrate preincubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0S85PubMed
TargetNuclear receptor corepressor 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50544211(CHEMBL4641682)copy SMILEScopy InChI
Affinity DataIC50: 0.0870nMAssay Description:Inhibition of full length human recombinant FLAG-tagged HDAC3/His6-tagged SMRT (1 to 899 residues) expressed in HEK293F cells using FLUOR DE LYS as s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0S85PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50544211(CHEMBL4641682)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of HDAC6 (unknown origin) using FLUOR DE LYS as substrate preincubated for 3 hrs followed by substrate addition and measured after 60 mins...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0S85PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50544211(CHEMBL4641682)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant HDAC8 expressed in Escherichia coli using FLUOR DE LYS as substrate preincubated for 3 hrs followed by substrate addi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0S85PubMed
TargetHistone deacetylase 3(Homo sapiens (Human))TBA
LigandPNGBDBM50544211(CHEMBL4641682)copy SMILEScopy InChI
Affinity DataIC50: 0.0870nMAssay Description:Inhibition of human recombinant full length FLAG-tagged HDAC3 expressed in HEK293F cells in using BML-KI104 as substrate in presence of SAHA as inhib...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8RDRPubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50544211(CHEMBL4641682)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of HDAC4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0S85PubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50544211(CHEMBL4641682)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human recombinant full length N-terminal GST-tagged HDAC5 expressed in baculovirus infected sf9 insect cells using Boc-Lys(TFA)-AMC as ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0S85PubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50544211(CHEMBL4641682)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of HDAC7 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0S85PubMed
TargetHistone deacetylase 11(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50544211(CHEMBL4641682)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human recombinant untagged HDAC11 expressed in baculovirus infected Sf9 insect cells using Boc-Lys(TFA)-AMC as substrate preincubated f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0S85PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50544211(CHEMBL4641682)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human recombinant full length FLAG-tagged HDAC1 expressed in HEK293F cells using BML-KI104 as substrate in presence of SAHA as inhibito...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8RDRPubMed
TargetHistone deacetylase 1/2/3/8(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50544211(CHEMBL4641682)copy SMILEScopy InChI
Affinity DataEC50:  4.70nMAssay Description:Inhibition of class 1 HDAC in human Jurkat model of HIV latency assessed as reactivation of HIV latency incubated for 20 hrs in presence of 5% NHS by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0S85PubMed