null

SMILES COc1cc(cc(OC)c1OC)-c1cncc(c1C)-c1ccc(cc1)C1CCN(C)CC1

InChI Key InChIKey=CNEAZWBYXISKKK-UHFFFAOYSA-N

PDB links: 45 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50544413   

TargetActivin receptor type-1(Homo sapiens (Human))
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50544413(CHEMBL4633241)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of [gamma-33P]-ATP by radiometric hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50544413(CHEMBL4633241)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human ALK5 using casein as substrate in presence of [gamma-33P]-ATP by radiometric hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4GV3PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50544413(CHEMBL4633241)copy SMILEScopy InChI
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of human ERG expressed in HEK293 cells after 5 mins by IonWorks barracuda patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4GV3PubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50544413(CHEMBL4633241)copy SMILEScopy InChI
Affinity DataIC50: 3.33E+3nMAssay Description:Inhibition of recombinant human ALK5 expressed in HEK293 cells transfected with CAGA-luciferase and Renilla luciferase reporter after 24 hrs by dual ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4GV3PubMed
TargetActivin receptor type-1B(Homo sapiens (Human))
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50544413(CHEMBL4633241)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human ALK4 using casein as substrate in presence of [gamma-33P]-ATP by radiometric hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4GV3PubMed
TargetActivin receptor type-1(Homo sapiens (Human))
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50544413(CHEMBL4633241)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Competitive displacement of PBI-6908 from nanoluciferase-fused ALK2 (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET NanoGl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB