null

SMILES CC1CCN(CC1c1cc(nc2ncnn12)C(F)F)C(=O)c1ccc2occc2c1

InChI Key

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50547752   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))TBA

LigandBDBM50547752(CHEMBL4797113)copy SMILES

Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE4D3 expressed in Sf9 cells by scintillation counting methodMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z194SPubMed

TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B(Homo sapiens (Human))TBA

LigandBDBM50547752(CHEMBL4797113)copy SMILES

Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE1B1 expressed in HEK cells by scintillation counting methodMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z194SPubMed

TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Homo sapiens (Human))TBA

LigandBDBM50547752(CHEMBL4797113)copy SMILES

Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE11A4 expressed in HEK cells by scintillation counting methodMore data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z194SPubMed

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))TBA

LigandBDBM50547752(CHEMBL4797113)copy SMILES

Affinity DataIC50: 2.24E+3nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE3A expressed in Sf9 cells in presence of [3H]-cAMP and cAMP incubated for 60 mins by scintillation co...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z194SPubMed

TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))TBA

LigandBDBM50547752(CHEMBL4797113)copy SMILES

Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE7A1 expressed in Sf9 cells by scintillation counting methodMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z194SPubMed

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))TBA

LigandBDBM50547752(CHEMBL4797113)copy SMILES

Affinity DataIC50: 1.10nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z194SPubMed