null

SMILES Cc1nc2nc(C)cc(C3CCCN(C3)C(=O)c3cc4CCCCc4s3)n2n1

InChI Key

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50547783   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))TBA

LigandBDBM50547783(CHEMBL4757440)copy SMILES

Affinity DataIC50: 562nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z194SPubMed

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))TBA

LigandBDBM50547783(CHEMBL4757440)copy SMILES

Affinity DataIC50: 100nMAssay Description:Inhibition of 6xHis-tagged rat recombinant PDE10A2 expressed in Sf9 cells in presence of [3H]-cAMP and cAMP incubated for 60 mins by scintillation co...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z194SPubMed

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))TBA

LigandBDBM50547783(CHEMBL4757440)copy SMILES

Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE3A expressed in Sf9 cells in presence of [3H]-cAMP and cAMP incubated for 60 mins by scintillation co...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z194SPubMed