null

SMILES O=C1NCc2c(c[nH]c12)-c1cnc2[nH]cc(Cc3ccccc3)c2c1

InChI Key

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50549944   

TargetHepatocyte growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50549944(CHEMBL4747073)copy SMILES
Affinity DataKd:  5.30E+3nMAssay Description:Binding affinity to folded P-loop conformation of wild type N-terminal NH-tagged and avi-tagged dephosphorylated human c-MET (956 to 1390 residues) e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHepatocyte growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50549944(CHEMBL4747073)copy SMILES
Affinity DataIC50: 2.19E+4nMAssay Description:Inhibition of c-Met phosphorylation at Tyr 1234/Tyr1235 residues in human NCI-H1993 cells incubated for 4 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHepatocyte growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50549944(CHEMBL4747073)copy SMILES
Affinity DataIC50: 660nMAssay Description:Inhibition of wild type N-terminal NH-tagged and avi-tagged dephosphorylated human c-MET (956 to 1390 residues) expressed in Sf21 cells using poly (G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB