null

SMILES COC[C@H](NC(=O)[C@H](CCC(=O)NC(C)(C)C)NS(=O)(=O)c1ccc(C)cc1)C(=O)NCc1ccc(F)c2ccccc12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50554397   

TargetProteasome subunit beta type-8(Homo sapiens (Human))TBA
LigandPNGBDBM50554397(CHEMBL4741140)copy SMILES
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human 20S immunoproteasome beta 5 chymotrypsin-like activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3WB6PubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))TBA
LigandPNGBDBM50554397(CHEMBL4741140)copy SMILES
Affinity DataIC50: 1.86E+3nMAssay Description:Inhibition of human 20S constitutive proteasome beta 5 chymotrypsin-like activity in human HeLa cells incubated for 2 hrs by proteasome-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3WB6PubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))TBA
LigandPNGBDBM50554397(CHEMBL4741140)copy SMILES
Affinity DataIC50: 28nMAssay Description:Inhibition of human 20S immunoproteasome beta 5 chymotrypsin-like activity in human KARPAS-1106P cells incubated for 2 hrs by proteasome-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3WB6PubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))TBA
LigandPNGBDBM50554397(CHEMBL4741140)copy SMILES
Affinity DataIC50: 1.46E+3nMAssay Description:Inhibition of human constitutive 20S proteasome beta 5 chymotrypsin-like activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3WB6PubMed