null
SMILES Oc1ccc(Nc2cc(Nc3ccc(cc3)C#N)nc(n2)-c2ccccc2)cc1
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50557279
Affinity DataIC50: 387nMAssay Description:Inhibition of ABCG2 (unknown origin) expressed in MDCK-II cells assessed as reduction in pheophorbide A efflux measured after 2 hrs by flow cytometryMore data for this Ligand-Target Pair
Affinity DataEC50: 171nMAssay Description:Inhibition of ABCG2 (unknown origin) expressed in MDCK-II cells assessed as potentiation of SN-38-induced cytotoxicity measured after 72 hrs by MTT a...More data for this Ligand-Target Pair
Affinity DataIC50: 4.04E+3nMAssay Description:Inhibition of ABCC1 (unknown origin) expressed in human NCI-H69AR cells assessed as reduction in calcein AM efflux preincubated for 30 mins followed ...More data for this Ligand-Target Pair
Affinity DataIC50: 4.54E+3nMAssay Description:Inhibition of ABCB1 (unknown origin) expressed in human A2780 ADR cells assessed as reduction in calcein AM efflux preincubated for 30 mins followed ...More data for this Ligand-Target Pair