null

SMILES Fc1ccc(CNc2nc(nc3cc(ccc23)-c2cccs2)N2CCOCC2)cc1F

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50557577   

TargetProstaglandin G/H synthase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50557577(CHEMBL4795293)copy SMILES
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human recombinant COX-2 assessed as reduction in PGE2 production using 10 uM arachidonic acid as substrate preincubated with enzyme for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP56Z1PubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))TBA
LigandPNGBDBM50557577(CHEMBL4795293)copy SMILES
Affinity DataIC50: 1.39E+3nMAssay Description:Inhibition of ovine COX-1 assessed as reduction in PGE2 production using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP56Z1PubMed