null

SMILES CC(=O)N[C@@H]1C[C@H](N)CC[C@@H]1N1CC[C@H](Nc2ncnc3ccc(cc23)C(F)(F)F)C1=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50557871   

TargetC-C chemokine receptor type 2(Homo sapiens (Human))TBA
LigandPNGBDBM50557871(CHEMBL4757452)copy SMILES
Affinity DataIC50: 2.90nMAssay Description:Displacement of [125I]MCP1 from CCR2 in human PBMC measured after 30 mins by Microscintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0JS9PubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))TBA
LigandPNGBDBM50557871(CHEMBL4757452)copy SMILES
Affinity DataIC50: 3nMAssay Description:Antagonist activity at CCR2 in human THP1 cells assessed as reduction in MCP1-induced chemotaxis measured after 30 mins by calcein-AM dye based fluor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0JS9PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))TBA
LigandPNGBDBM50557871(CHEMBL4757452)copy SMILES
Affinity DataIC50: 1.87E+4nMAssay Description:Antagonist activity at CCR5 in human HT1080 cell membrane assessed as inhibition of [125I]MIP1beta-binding incubated for 4 to 6 hrs by topcount assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0JS9PubMed