null

SMILES ONC(=O)c1ccc(CCCN2CCC(CN[C@H]3C[C@@H]3c3ccccc3)CC2)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50559388   

TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50559388(CHEMBL4749146)copy SMILES
Affinity DataIC50: 6nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8BBHPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50559388(CHEMBL4749146)copy SMILES
Affinity DataIC50: 48nMAssay Description:Antagonist activity against Tachykinin receptor 2 was measured by Rabbit pulmonary artery(RPA) assay.More data for this Ligand-Target Pair
In DepthDetails
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50559388(CHEMBL4749146)copy SMILES
Affinity DataIC50: 69nMAssay Description:Inhibition of human HDAC6 (unknown origin) using RHKKAc as substrate by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8BBHPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50559388(CHEMBL4749146)copy SMILES
Affinity DataIC50: 69nMAssay Description:Inhibition of human HDAC6 (unknown origin) using RHKKAc as substrate by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8BBHPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50559388(CHEMBL4749146)copy SMILES
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of human HDAC1 using RHKKAc as substrate by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8BBHPubMed
TargetHistone deacetylase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50559388(CHEMBL4749146)copy SMILES
Affinity DataIC50: 3.95E+3nMAssay Description:Inhibition of human HDAC2 using RHKKAc as substrate by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8BBHPubMed
LigandPNGBDBM50559388(CHEMBL4749146)copy SMILES
Affinity DataIC50: 7.47E+3nMAssay Description:Inhibition of human HDAC3/NCOR2 using RHKKAc as substrate by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8BBHPubMed
TargetHistone deacetylase 5(Homo sapiens (Human))TBA
LigandPNGBDBM50559388(CHEMBL4749146)copy SMILES
Affinity DataIC50: 1.14E+3nMAssay Description:Inhibition of human HDAC5 using Boc-Lys(trifluoroacetyl)-AMC as substrate by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8BBHPubMed
TargetHistone deacetylase 7(Homo sapiens (Human))TBA
LigandPNGBDBM50559388(CHEMBL4749146)copy SMILES
Affinity DataIC50: 3.58E+3nMAssay Description:Inhibition of human HDAC7 using Boc-Lys(trifluoroacetyl)-AMC as substrate by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8BBHPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))TBA
LigandPNGBDBM50559388(CHEMBL4749146)copy SMILES
Affinity DataIC50: 71nMAssay Description:Inhibition of human HDAC8 using RHKAcKAc as substrate by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8BBHPubMed
TargetHistone deacetylase 9(Homo sapiens (Human))TBA
LigandPNGBDBM50559388(CHEMBL4749146)copy SMILES
Affinity DataIC50: 3.43E+3nMAssay Description:Inhibition of human HDAC9 using Boc-Lys(trifluoroacetyl)-AMC as substrate by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8BBHPubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))TBA
LigandPNGBDBM50559388(CHEMBL4749146)copy SMILES
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC10 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8BBHPubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))TBA
LigandPNGBDBM50559388(CHEMBL4749146)copy SMILES
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of MAO-A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8BBHPubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))TBA
LigandPNGBDBM50559388(CHEMBL4749146)copy SMILES
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of MAO-B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8BBHPubMed
LigandPNGBDBM50559388(CHEMBL4749146)copy SMILES
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8BBHPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50559388(CHEMBL4749146)copy SMILES
Affinity DataIC50: 5nMAssay Description:Antagonist activity against Tachykinin receptor 2 was measured by Hamster isolated trachea(HT) assay.More data for this Ligand-Target Pair
In DepthDetails
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50559388(CHEMBL4749146)copy SMILES
Affinity DataIC50: 6nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8BBHPubMed