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SMILES Cc1cc(-c2cnc3cc(ccn23)-c2ccc(cc2)N2CCNCC2)c2cc(F)ccc2n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50560467   

TargetActivin receptor type-1(Homo sapiens (Human))TBA
LigandPNGBDBM50560467(CHEMBL4788859)copy SMILES
Affinity DataIC50: 11nMAssay Description:Inhibition of human ALK2 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7NDJPubMed
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))TBA
LigandPNGBDBM50560467(CHEMBL4788859)copy SMILES
Affinity DataIC50: 166nMAssay Description:Inhibition of human ALK1 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7NDJPubMed
TargetBone morphogenetic protein receptor type-1A(Homo sapiens (Human))TBA
LigandPNGBDBM50560467(CHEMBL4788859)copy SMILES
Affinity DataIC50: 5nMAssay Description:Inhibition of human ALK3 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7NDJPubMed
TargetActivin receptor type-1B(Homo sapiens (Human))TBA
LigandPNGBDBM50560467(CHEMBL4788859)copy SMILES
Affinity DataIC50: 569nMAssay Description:Inhibition of human ALK4 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7NDJPubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))TBA
LigandPNGBDBM50560467(CHEMBL4788859)copy SMILES
Affinity DataIC50: 7.45E+3nMAssay Description:Inhibition of human PDGFRbeta using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7NDJPubMed
TargetBone morphogenetic protein receptor type-1B(Homo sapiens (Human))TBA
LigandPNGBDBM50560467(CHEMBL4788859)copy SMILES
Affinity DataIC50: 29nMAssay Description:Inhibition of human ALK6 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7NDJPubMed
TargetBone morphogenetic protein receptor type-2(Homo sapiens (Human))TBA
LigandPNGBDBM50560467(CHEMBL4788859)copy SMILES
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human BMPR2 using MBP as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7NDJPubMed
TargetTGF-beta receptor type-2(Homo sapiens (Human))TBA
LigandPNGBDBM50560467(CHEMBL4788859)copy SMILES
Affinity DataIC50: 587nMAssay Description:Inhibition of human TGFBR2 using MBP as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7NDJPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))TBA
LigandPNGBDBM50560467(CHEMBL4788859)copy SMILES
Affinity DataIC50: 1.34E+4nMAssay Description:Inhibition of human KDR using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7NDJPubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))TBA
LigandPNGBDBM50560467(CHEMBL4788859)copy SMILES
Affinity DataIC50: 1.27E+3nMAssay Description:Inhibition of human ALK5 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7NDJPubMed