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SMILES C(COc1ccc(Cc2ccccc2)cc1)CN1CCN(CC1)c1ccncc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50562549   

TargetHistamine H3 receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50562549(CHEMBL4786308)copy SMILES
Affinity DataKi:  18nMAssay Description:Displacement of [3H]UR-PI294 from human SP-FLAG-tagged H3R expressed in HEK293T cells measured after 60 to 120 mins by liquid scintillation counting ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP570WPubMed
TargetHistamine H1 receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50562549(CHEMBL4786308)copy SMILES
Affinity DataKi:  4.24E+3nMAssay Description:Displacement of [3H]mepyramine from human H1R expressed in Sf9 cell membranes co-expressing RGS4 measured after 60 mins by scintillation counting ana...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP570WPubMed
TargetHistamine H2 receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50562549(CHEMBL4786308)copy SMILES
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]UR-DE257 from Gsalphas-coupled human H2R expressed in Sf9 cell membranes measured after 60 mins by scintillation counting analysi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP570WPubMed
TargetHistamine H4 receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50562549(CHEMBL4786308)copy SMILES
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]histamine from Gialpha2/Gbeta1gamma2-coupled human H4R expressed in Sf9 cell membranes measured after 60 mins by scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP570WPubMed