null

SMILES Oc1cc(ccc1F)-c1nc([nH]c1-c1ccnc(NCCCNS(=O)(=O)c2ccccc2)n1)-c1ccccc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50563427   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))TBA
LigandPNGBDBM50563427(CHEMBL4758203)copy SMILES
Affinity DataIC50: 210nMAssay Description:Inhibition of p38 alpha (unknown origin) using Ser/Thr 15 as substrate incubated for 1 hr in presence of ATP by Z'-Lyte assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0M8QPubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))TBA
LigandPNGBDBM50563427(CHEMBL4758203)copy SMILES
Affinity DataIC50: 5.60nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin) using Ser/Thr 03 as substrate after 1 hr in presence of ATP by Z'-LYTE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0M8QPubMed