null

SMILES Nc1ccccc1NC(=O)c1ccc(Cn2cnc3c(Nc4ccc(F)c(Cl)c4)nc(Cl)nc23)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50564436   

TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50564436(CHEMBL4784684)copy SMILES
Affinity DataIC50: 685nMAssay Description:Inhibition of human recombinant HDAC1 expressed in baculovirus using fluorogenic peptide p53 residues 379-382 (RHKK(Ac)AMC) as substrate by Fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9FT0PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))TBA
LigandPNGBDBM50564436(CHEMBL4784684)copy SMILES
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant HDAC8 expressed in baculovirus using fluorogenic peptide p53 residues 379-382 (RHKK(Ac)AMC) as substrate by Fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9FT0PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50564436(CHEMBL4784684)copy SMILES
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant HDAC6 expressed in baculovirus using fluorogenic peptide p53 residues 379-382 (RHKK(Ac)AMC) as substrate by Fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9FT0PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50564436(CHEMBL4784684)copy SMILES
Affinity DataIC50: 3.78E+3nMAssay Description:Inhibition of human recombinant HDAC2 expressed in baculovirus using fluorogenic peptide p53 residues 379-382 (RHKK(Ac)AMC) as substrate by Fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9FT0PubMed