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SMILES CCc1cc(Nc2nc(NCc3ccc(F)cn3)nc3cccc(OC)c23)n[nH]1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50566947   

TargetG protein-coupled receptor kinase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50566947(CHEMBL4847703)copy SMILES
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant full-length human GRK6 using casein as substrate measured after 80 mins in presence of [gamma33P]ATP by radiometric scintil...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K2D97PubMed
TargetAurora kinase A(Homo sapiens (Human))TBA
LigandPNGBDBM50566947(CHEMBL4847703)copy SMILES
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of recombinant full length human Aurora A using LRRASLG as substrate incubated for 40 mins in presence of [gamma-33ATP] by radiometric sci...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K2D97PubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50566947(CHEMBL4847703)copy SMILES
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human IGF-1R (959 to end residues) using KKKSPGEYVNIEF as substrate incubated for 40 mins in presence of [gamma-33ATP] by r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K2D97PubMed
TargetRhodopsin kinase GRK1(Homo sapiens (Human))TBA
LigandPNGBDBM50566947(CHEMBL4847703)copy SMILES
Affinity DataIC50: 450nMAssay Description:Inhibition of human GRK1 using casein as substrate in presence of [gamma33P]ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K2D97PubMed
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50566947(CHEMBL4847703)copy SMILES
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human GRK2 using casein as substrate in presence of [gamma33P]ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K2D97PubMed
TargetG protein-coupled receptor kinase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50566947(CHEMBL4847703)copy SMILES
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to FLAG-tagged GRK6 in human KMS11 cells incubated for 2.5 hrs by ITDR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K2D97PubMed
TargetG protein-coupled receptor kinase 4(Homo sapiens (Human))TBA
LigandPNGBDBM50566947(CHEMBL4847703)copy SMILES
Affinity DataIC50: 190nMAssay Description:Inhibition of human GRK4 using casein as substrate in presence of [gamma33P]ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K2D97PubMed
TargetG protein-coupled receptor kinase 5(Homo sapiens (Human))TBA
LigandPNGBDBM50566947(CHEMBL4847703)copy SMILES
Affinity DataIC50: 51nMAssay Description:Inhibition of recombinant full length human GRK5 using casein as substrate incubated for 40 mins in presence of [gamma-33ATP] by scintillation counti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K2D97PubMed
TargetG protein-coupled receptor kinase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50566947(CHEMBL4847703)copy SMILES
Affinity DataIC50: 33nMAssay Description:Inhibition of human GRK6 using casein as substrate in presence of [gamma33P]ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K2D97PubMed
TargetRhodopsin kinase GRK7(Homo sapiens (Human))TBA
LigandPNGBDBM50566947(CHEMBL4847703)copy SMILES
Affinity DataIC50: 36nMAssay Description:Inhibition of recombinant full length human GRK7 using casein as substrate incubated for 40 mins in presence of [gamma-33ATP] by scintillation counti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K2D97PubMed
TargetBeta-adrenergic receptor kinase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50566947(CHEMBL4847703)copy SMILES
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human GRK3 using casein as substrate in presence of [gamma33P]ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K2D97PubMed