null

SMILES Oc1c(F)cc(Nc2ncc3ncn(-c4ccc(CCN5CCOCC5)cc4)c3n2)cc1F

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50568106   

TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))TBA
LigandPNGBDBM50568106(CHEMBL4849660 | US11851436, Compound A1-4)copy SMILES
Affinity DataIC50: 18nMAssay Description:Inhibition of RSK2 (unknown origin) using Ulight-rpS6 as substrate incubated for 1 hr in presence of ATP by TR FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70KKBPubMed
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))TBA
LigandPNGBDBM50568106(CHEMBL4849660 | US11851436, Compound A1-4)copy SMILES
Affinity DataIC50: 329nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))TBA
LigandPNGBDBM50568106(CHEMBL4849660 | US11851436, Compound A1-4)copy SMILES
Affinity DataEC50:  1.90E+3nMAssay Description:Inhibition of RSK2 in human MOLM-13 assessed as reduction in cell viability measured after 72 hrs by MTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70KKBPubMed