null

SMILES Cl.COc1ccc2nc3CCCc3c(N)c2c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50569764   

TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50569764(CHEMBL4855357)copy SMILES
Affinity DataIC50: 8.22E+3nMAssay Description:Inhibition of human recombinant AChE assessed as reduction in cholinesterase activity using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC365GPubMed
TargetCholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50569764(CHEMBL4855357)copy SMILES
Affinity DataIC50: 1.06E+4nMAssay Description:Inhibition of human plasmatic BuChE assessed as reduction in cholinesterase activity by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC365GPubMed
LigandPNGBDBM50569764(CHEMBL4855357)copy SMILES
Affinity DataIC50: 8.89E+4nMAssay Description:Inhibition of human GluN1a/GluN2B receptor expressed in HEK293 cells assessed as relative inhibition of glycine/glutamate-induced current measured at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC365GPubMed
LigandPNGBDBM50569764(CHEMBL4855357)copy SMILES
Affinity DataIC50: 1.46E+4nMAssay Description:Inhibition of human GluN1a/GluN2B receptor expressed in HEK293 cells assessed as inhibition of glycine/glutamate-induced current measured at -60 mV h...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC365GPubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Homo sapiens (Human))TBA
LigandPNGBDBM50569764(CHEMBL4855357)copy SMILES
Affinity DataIC50: 6.68E+4nMAssay Description:Inhibition of human GluN1a/GluN2A receptor expressed in HEK293 cells assessed as relative inhibition of glycine/glutamate-induced current measured at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC365GPubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Homo sapiens (Human))TBA
LigandPNGBDBM50569764(CHEMBL4855357)copy SMILES
Affinity DataIC50: 4.16E+3nMAssay Description:Inhibition of human GluN1a/GluN2A receptor expressed in HEK293 cells assessed as inhibition of glycine/glutamate-induced current measured at -60 mV h...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC365GPubMed