null

SMILES CN1CCC(CC(=O)Nc2cc(Oc3ccc(NC(=O)c4cn(C5CCCC5)c(=O)n(-c5ccc(F)cc5)c4=O)cc3F)ccn2)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50571012   

TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))TBA
LigandPNGBDBM50571012(CHEMBL4867696)copy SMILES
Affinity DataIC50: 1.10nMAssay Description:Inhibition of recombinant human GST-tagged Axl incubated for 1 hr by ADP-glo based luminometry analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6Q46PubMed
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))TBA
LigandPNGBDBM50571012(CHEMBL4867696)copy SMILES
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human Mer expressed in mouse BaF3 cells assessed as reduction in cell viability incubated for 2 days by cell titer glo assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6Q46PubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))TBA
LigandPNGBDBM50571012(CHEMBL4867696)copy SMILES
Affinity DataIC50: 2.80nMAssay Description:Inhibition of recombinant human Axl expressed in mouse BaF3 cells assessed as reduction in cell viability incubated for 2 days by cell titer glo assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6Q46PubMed
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))TBA
LigandPNGBDBM50571012(CHEMBL4867696)copy SMILES
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human GST-tagged Mer using biotinylated peptide as substrate incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6Q46PubMed