null

SMILES CN1CCN(CC1)C1CCN(CC1)C(=O)Nc1cc(Oc2cc(F)c(NC(=O)c3cc4C(=O)CCCc4n(-c4ccccc4)c3=O)cc2F)ccn1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50571018   

TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))TBA
LigandPNGBDBM50571018(CHEMBL4849679)copy SMILES
Affinity DataIC50: 1.30nMAssay Description:Inhibition of recombinant human GST-tagged Axl incubated for 1 hr by ADP-glo based luminometry analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6Q46PubMed
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))TBA
LigandPNGBDBM50571018(CHEMBL4849679)copy SMILES
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human Mer expressed in mouse BaF3 cells assessed as reduction in cell viability incubated for 2 days by cell titer glo assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6Q46PubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))TBA
LigandPNGBDBM50571018(CHEMBL4849679)copy SMILES
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human Axl expressed in mouse BaF3 cells assessed as reduction in cell viability incubated for 2 days by cell titer glo assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6Q46PubMed
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))TBA
LigandPNGBDBM50571018(CHEMBL4849679)copy SMILES
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant human GST-tagged Mer using biotinylated peptide as substrate incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6Q46PubMed