null

SMILES [H][C@]12C[C@@]1([H])[C@H](Cc1ccccc1)N(C2)c1cc(cc(=O)[nH]1)N1CCO[C@H](C)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50571470   

TargetSerine-protein kinase ATM(Homo sapiens (Human))TBA
LigandPNGBDBM50571470(CHEMBL4869283 | US11685734, Example 41)copy SMILES
Affinity DataKi:  11nMAssay Description:Inhibition of full length recombinant FLAG-tagged human ATM assessed as decrease in p53 S15 phosphorylation using full length myc-tagged p53 as subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76HB1PubMed
LigandPNGBDBM50571470(CHEMBL4869283 | US11685734, Example 41)copy SMILES
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of full length recombinant GST-tagged human VPS34 expressed in baculovirus expression system using PI/PS as substrate incubated for 60 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76HB1PubMed
TargetSerine-protein kinase ATM(Homo sapiens (Human))TBA
LigandPNGBDBM50571470(CHEMBL4869283 | US11685734, Example 41)copy SMILES
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of ATM in human U2OS cells assessed as reduction in etoposide-stimulated KAP1 phosphorylation incubated for 60 mins by immunoreactivity as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76HB1PubMed
TargetSerine-protein kinase ATM(Homo sapiens (Human))TBA
LigandPNGBDBM50571470(CHEMBL4869283 | US11685734, Example 41)copy SMILES
Affinity DataIC50: 69.1nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q803G