null

SMILES F\C(=C/[C@H](CCc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccncc1)S(=O)(=O)Oc1ccccc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50574815   

TargetCysteine protease(Trypanosoma brucei rhodesiense)TBA
LigandPNGBDBM50574815(CHEMBL4857486)copy SMILES
Affinity DataKi:  15nMAssay Description:Inhibition of Trypanosoma brucei rhodesain assessed as fluorescence using Cbz-Phe-Arg-AMC as substrate measured using Dixon equation by fluorometric ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC14G4PubMed
TargetProcathepsin L(Homo sapiens (Human))TBA
LigandPNGBDBM50574815(CHEMBL4857486)copy SMILES
Affinity DataKi:  60nMAssay Description:Inhibition of human CatL assessed as fluorescence using Cbz-Phe-Arg-AMC as substrate measured using Dixon equation by fluorometric enzyme assaysMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC14G4PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)TBA
LigandPNGBDBM50574815(CHEMBL4857486)copy SMILES
Affinity DataKi:  98nMAssay Description:Inhibition of Trypanosoma brucei rhodesain assessed as fluorescence using Cbz-Phe-Arg-AMC as substrate measured at second inhibition step by fluorome...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC14G4PubMed
TargetProcathepsin L(Homo sapiens (Human))TBA
LigandPNGBDBM50574815(CHEMBL4857486)copy SMILES
Affinity DataKi:  258nMAssay Description:Inhibition of human liver CatL assessed as fluorescence using Cbz-Phe-Arg-AMC as substrate measured at second inhibition step by fluorometric enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC14G4PubMed
TargetCathepsin B(Homo sapiens (Human))TBA
LigandPNGBDBM50574815(CHEMBL4857486)copy SMILES
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition of human liver CatB assessed as fluorescence using Cbz-Phe-Arg-AMC as substrate by fluorometric enzyme assaysMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC14G4PubMed