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SMILES Cn1cncc1-c1cc(F)ccc1CN1CCP(O)(=O)[C@@](CCCCN)(C1)C(O)=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50575780   

TargetCarboxypeptidase B2(Homo sapiens (Human))TBA
LigandPNGBDBM50575780(CHEMBL4878039)copy SMILES
Affinity DataKi:  0.75nMAssay Description:Inhibition of recombinant human activated TAFI incubated for 45 mins using hippuryl-arginine as substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB49JMPubMed
TargetCarboxypeptidase B(Homo sapiens (Human))TBA
LigandPNGBDBM50575780(CHEMBL4878039)copy SMILES
Affinity DataKi:  5.30E+3nMAssay Description:Inhibition of recombinant human pancreatic CPB incubated for 25 mins using hippuryl-arginine as substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB49JMPubMed
TargetCarboxypeptidase N catalytic chain(Homo sapiens (Human))TBA
LigandPNGBDBM50575780(CHEMBL4878039)copy SMILES
Affinity DataKi:  2.82E+5nMAssay Description:Inhibition of recombinant human plasma CPN incubated for 25 mins using hippuryl-arginine as substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB49JMPubMed
TargetCarboxypeptidase B2(Rattus norvegicus)TBA
LigandPNGBDBM50575780(CHEMBL4878039)copy SMILES
Affinity DataEC50:  389nMAssay Description:Inhibition of TAFI in Sprague-Dawley rat blood TAFI incubated for 2 mins using hippuryl-arginine as substrate by thromboelastometry analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB49JMPubMed
TargetCarboxypeptidase B2(Homo sapiens (Human))TBA
LigandPNGBDBM50575780(CHEMBL4878039)copy SMILES
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human activated TAFI incubated for 45 mins using hippuryl-arginine as substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB49JMPubMed