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SMILES CNc1cc(Oc2ccc(NC(=O)Nc3cccc(c3)C(F)(F)F)c(F)c2)ncn1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50578218   

TargetSerine/threonine-protein kinase TNNI3K(Homo sapiens (Human))TBA
LigandPNGBDBM50578218(CHEMBL4863203)copy SMILES
Affinity DataIC50: 63nMAssay Description:Inhibition of TNNI3K (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8BG9PubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))TBA
LigandPNGBDBM50578218(CHEMBL4863203)copy SMILES
Affinity DataIC50: 63nMAssay Description:Inhibition of B-Raf (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8BG9PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))TBA
LigandPNGBDBM50578218(CHEMBL4863203)copy SMILES
Affinity DataIC50: 400nMAssay Description:Inhibition of p38alpha (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8BG9PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))TBA
LigandPNGBDBM50578218(CHEMBL4863203)copy SMILES
Affinity DataIC50: 6.30nMAssay Description:Inhibition of GST-6His tagged VEGFR2 (unknown origin) using biotin-aminohexyl-EEEEYFELVAKKKK-NH2 peptide substrate incubated for 90 mins by HTRF assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8BG9PubMed