null

SMILES CCn1c(nc2nc(OC)c(cc12)-c1nnn[nH]1)C(O)(c1ccccc1F)c1ccccc1F

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50578401   

LigandPNGBDBM50578401(CHEMBL4870590 | US20240009175, Compound 57)copy SMILES
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of human recombinant ACSS2 assessed as AMP release using Coenzyme A/ATP as co-substrates by AMP Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76HCGPubMed
LigandPNGBDBM50578401(CHEMBL4870590 | US20240009175, Compound 57)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM50578401(CHEMBL4870590 | US20240009175, Compound 57)copy SMILES
Affinity DataIC50: 1nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into histones measured after 24 hrs by scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76HCGPubMed
LigandPNGBDBM50578401(CHEMBL4870590 | US20240009175, Compound 57)copy SMILES
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into fatty acids measured after 24 hrs by scintillation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76HCGPubMed