null

SMILES COc1cc(ccc1NC(=O)c1cccc(n1)-c1ccn[nH]1)N1CCC(CC1)OCC(=O)N[C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)N[C@@H](C)c1ccc(cc1)-c1scnc1C)C(C)(C)C

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50579722   

TargetInterleukin-1 receptor-associated kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50579722(CHEMBL4762381)copy SMILES
Affinity DataIC50: 72nMAssay Description:Inhibition of truncated human N-terminal GST-fusion tagged IRAK1 (194 to 712 residues) expressed in baculovirus expression system using FAM-labelled ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3XMHPubMed
Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))TBA
LigandPNGBDBM50579722(CHEMBL4762381)copy SMILES
Affinity DataIC50: 1.07E+3nMAssay Description:Displacement of 5-FAM-labelled DEALA-HypYIPMDDDFQLRSF peptide from VHL (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3XMHPubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))TBA
LigandPNGBDBM50579722(CHEMBL4762381)copy SMILES
Affinity DataIC50: 443nMAssay Description:Inhibition of full length human N-terminal GST-fusion tagged IRAK4 expressed in baculovirus expression system using FAM-labelled peptide as substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3XMHPubMed