null

SMILES OC(=O)c1ccc(O[C@H]2CC[C@@H](CC2)NC(=O)NC23CC4CC(F)(CC(C2)c2ccccc42)C3)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50581728   

TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50581728(CHEMBL5093683)copy SMILES
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human recombinant sEH using CMNPC as substrate incubated for 5 mins by fluorescent based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70KPPPubMed
TargetBifunctional epoxide hydrolase 2(Mus musculus (Mouse))TBA
LigandPNGBDBM50581728(CHEMBL5093683)copy SMILES
Affinity DataIC50: 0.5nMAssay Description:Inhibition of mouse recombinant sEH using CMNPC as substrate incubated for 5 mins by fluorescent based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70KPPPubMed
TargetCytochrome c oxidase subunit 2(Homo sapiens (Human))TBA
LigandPNGBDBM50581728(CHEMBL5093683)copy SMILES
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70KPPPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))TBA
LigandPNGBDBM50581728(CHEMBL5093683)copy SMILES
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant LOX-5 preincubated for 10 mins in presence of AA and ATP measured after 20 mins by fluorescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70KPPPubMed
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)TBA
LigandPNGBDBM50581728(CHEMBL5093683)copy SMILES
Affinity DataIC50: 0.400nMAssay Description:Inhibition of rat recombinant sEH using CMNPC as substrate incubated for 5 mins by fluorescent based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70KPPPubMed