null

SMILES [H][C@]12CC[C@]([H])(CC(C1)n1c(C)nnc1C(C)C)N2CC[C@H](NC(=O)C1CCC(F)(F)CC1)c1ccccc1

InChI Key

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50583789   

TargetC-C chemokine receptor type 5(Homo sapiens (Human))TBA
LigandPNGBDBM50583789(CHEMBL584744)copy SMILES
Affinity DataEC50:  18nMAssay Description:Inhibition of CCR5-mediated HIV-1 Bal entry in human GHOST CCR5 cells assessed as decrease in viral reverse transcriptase activity by measuring [3H]t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetC-C chemokine receptor type 5(Homo sapiens (Human))TBA
LigandPNGBDBM50583789(CHEMBL584744)copy SMILES
Affinity DataIC50: 0.770nMAssay Description:Antagonist activity at CCR5 (unknown origin) expressed in HOS cells co-expressing Gqi-5 assessed as inhibition CCL5-stimulated Ca2+ mobilization by c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB