null

SMILES FC1CN(CCC1c1cc2nc(Nc3cnn(C4CC4(F)F)c3Cl)ncc2cc1Cl)C1CCOC1

InChI Key

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50584330   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))TBA

LigandBDBM50584330(CHEMBL5070497)copy SMILES

Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of human ERG by voltage clamp assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9GZHPubMed

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))TBA

LigandBDBM50584330(CHEMBL5070497)copy SMILES

Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant N-terminal GST-fused LRRK2 G2109S mutant (970 to 2527 residues) (unknown origin) preincubated with enzyme for 15 mins follo...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9GZHPubMed