null

SMILES C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)COC(=O)CCC(=O)OCCc1ccc(cc1)C(CN)C(=O)Nc1ccc2cnccc2c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 511475   

TargetTumor necrosis factor(Homo sapiens (Human))TBA
LigandPNGBDBM511475(US11059789, Example 26 | US11691950, Example 26)copy SMILES
Affinity DataIC50: 227nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD72M2US Patent
TargetTumor necrosis factor(Homo sapiens (Human))TBA
LigandPNGBDBM511475(US11059789, Example 26 | US11691950, Example 26)copy SMILES
Affinity DataIC50: 227nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9