null

SMILES C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)COC(=O)C[C@H](N)C(=O)OCc1ccc(cc1)[C@@H](CN)C(=O)Nc1ccc2cnccc2c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 27 hits for monomerid = 511482   

TargetRho-associated protein kinase 2(Homo sapiens (Human))TBA
LigandPNGBDBM511482(US11059789, Example 83 | US11691950, Example 83)copy SMILES
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))TBA
LigandPNGBDBM511482(US11059789, Example 83 | US11691950, Example 83)copy SMILES
Affinity DataIC50: 95nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD72M2US Patent
LigandPNGBDBM511482(US11059789, Example 83 | US11691950, Example 83)copy SMILES
Affinity DataIC50: 29nMMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))TBA
LigandPNGBDBM511482(US11059789, Example 83 | US11691950, Example 83)copy SMILES
Affinity DataIC50: 3.47E+4nMMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))TBA
LigandPNGBDBM511482(US11059789, Example 83 | US11691950, Example 83)copy SMILES
Affinity DataIC50: 2.20E+4nMMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))TBA
LigandPNGBDBM511482(US11059789, Example 83 | US11691950, Example 83)copy SMILES
Affinity DataIC50: 7.73E+3nMMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))TBA
LigandPNGBDBM511482(US11059789, Example 83 | US11691950, Example 83)copy SMILES
Affinity DataIC50: 5.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9
LigandPNGBDBM511482(US11059789, Example 83 | US11691950, Example 83)copy SMILES
Affinity DataIC50: 1.92E+4nMMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9
TargetProtein kinase C eta type(Homo sapiens (Human))TBA
LigandPNGBDBM511482(US11059789, Example 83 | US11691950, Example 83)copy SMILES
Affinity DataIC50: 51nMMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9
TargetProtein kinase C delta type(Homo sapiens (Human))TBA
LigandPNGBDBM511482(US11059789, Example 83 | US11691950, Example 83)copy SMILES
Affinity DataIC50: 56nMMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9
TargetProtein kinase C epsilon type(Homo sapiens (Human))TBA
LigandPNGBDBM511482(US11059789, Example 83 | US11691950, Example 83)copy SMILES
Affinity DataIC50: 154nMMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))TBA
LigandPNGBDBM511482(US11059789, Example 83 | US11691950, Example 83)copy SMILES
Affinity DataIC50: 95nMMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))TBA
LigandPNGBDBM511482(US11059789, Example 83 | US11691950, Example 83)copy SMILES
Affinity DataIC50: 25nMMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9
LigandPNGBDBM511482(US11059789, Example 83 | US11691950, Example 83)copy SMILES
Affinity DataIC50: 1.00E+5nMMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))TBA
LigandPNGBDBM511482(US11059789, Example 83 | US11691950, Example 83)copy SMILES
Affinity DataIC50: 55nMMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9
TargetRho-associated protein kinase 2(Homo sapiens (Human))TBA
LigandPNGBDBM511482(US11059789, Example 83 | US11691950, Example 83)copy SMILES
Affinity DataIC50: 9nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD72M2US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM511482(US11059789, Example 83 | US11691950, Example 83)copy SMILES
Affinity DataIC50: 11nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD72M2US Patent
LigandPNGBDBM511482(US11059789, Example 83 | US11691950, Example 83)copy SMILES
Affinity DataIC50: 29nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD72M2US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))TBA
LigandPNGBDBM511482(US11059789, Example 83 | US11691950, Example 83)copy SMILES
Affinity DataIC50: 3.47E+4nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD72M2US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))TBA
LigandPNGBDBM511482(US11059789, Example 83 | US11691950, Example 83)copy SMILES
Affinity DataIC50: 2.20E+4nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD72M2US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))TBA
LigandPNGBDBM511482(US11059789, Example 83 | US11691950, Example 83)copy SMILES
Affinity DataIC50: 7.73E+3nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD72M2US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))TBA
LigandPNGBDBM511482(US11059789, Example 83 | US11691950, Example 83)copy SMILES
Affinity DataIC50: 5.00E+4nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD72M2US Patent
LigandPNGBDBM511482(US11059789, Example 83 | US11691950, Example 83)copy SMILES
Affinity DataIC50: 1.92E+4nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD72M2US Patent
TargetProtein kinase C alpha type(Homo sapiens (Human))TBA
LigandPNGBDBM511482(US11059789, Example 83 | US11691950, Example 83)copy SMILES
Affinity DataIC50: 51nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD72M2US Patent
TargetProtein kinase C delta type(Homo sapiens (Human))TBA
LigandPNGBDBM511482(US11059789, Example 83 | US11691950, Example 83)copy SMILES
Affinity DataIC50: 56nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD72M2US Patent
TargetProtein kinase C epsilon type(Homo sapiens (Human))TBA
LigandPNGBDBM511482(US11059789, Example 83 | US11691950, Example 83)copy SMILES
Affinity DataIC50: 154nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD72M2US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM511482(US11059789, Example 83 | US11691950, Example 83)copy SMILES
Affinity DataIC50: 11nMMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9