null

SMILES CC1(C)O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)COC(=O)CCC(=O)OCc1ccc(cc1)[C@@H](CN)C(=O)Nc1ccc2cnccc2c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 27 hits for monomerid = 511484   

TargetRho-associated protein kinase 2(Homo sapiens (Human))TBA
LigandPNGBDBM511484(US11059789, Example 33 | US11691950, Example 33)copy SMILES
Affinity DataIC50: 14nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))TBA
LigandPNGBDBM511484(US11059789, Example 33 | US11691950, Example 33)copy SMILES
Affinity DataIC50: 1.24E+3nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD72M2US Patent
LigandPNGBDBM511484(US11059789, Example 33 | US11691950, Example 33)copy SMILES
Affinity DataIC50: 81nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))TBA
LigandPNGBDBM511484(US11059789, Example 33 | US11691950, Example 33)copy SMILES
Affinity DataIC50: 5.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))TBA
LigandPNGBDBM511484(US11059789, Example 33 | US11691950, Example 33)copy SMILES
Affinity DataIC50: 4.24E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))TBA
LigandPNGBDBM511484(US11059789, Example 33 | US11691950, Example 33)copy SMILES
Affinity DataIC50: 3.01E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))TBA
LigandPNGBDBM511484(US11059789, Example 33 | US11691950, Example 33)copy SMILES
Affinity DataIC50: 5.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9
LigandPNGBDBM511484(US11059789, Example 33 | US11691950, Example 33)copy SMILES
Affinity DataIC50: 4.01E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9
TargetProtein kinase C eta type(Homo sapiens (Human))TBA
LigandPNGBDBM511484(US11059789, Example 33 | US11691950, Example 33)copy SMILES
Affinity DataIC50: 145nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9
TargetProtein kinase C delta type(Homo sapiens (Human))TBA
LigandPNGBDBM511484(US11059789, Example 33 | US11691950, Example 33)copy SMILES
Affinity DataIC50: 142nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9
TargetProtein kinase C epsilon type(Homo sapiens (Human))TBA
LigandPNGBDBM511484(US11059789, Example 33 | US11691950, Example 33)copy SMILES
Affinity DataIC50: 1.58E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))TBA
LigandPNGBDBM511484(US11059789, Example 33 | US11691950, Example 33)copy SMILES
Affinity DataIC50: 1.24E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))TBA
LigandPNGBDBM511484(US11059789, Example 33 | US11691950, Example 33)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9
LigandPNGBDBM511484(US11059789, Example 33 | US11691950, Example 33)copy SMILES
Affinity DataIC50: 5.52E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))TBA
LigandPNGBDBM511484(US11059789, Example 33 | US11691950, Example 33)copy SMILES
Affinity DataIC50: 103nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9
TargetRho-associated protein kinase 2(Homo sapiens (Human))TBA
LigandPNGBDBM511484(US11059789, Example 33 | US11691950, Example 33)copy SMILES
Affinity DataIC50: 14nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD72M2US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM511484(US11059789, Example 33 | US11691950, Example 33)copy SMILES
Affinity DataIC50: 21nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD72M2US Patent
LigandPNGBDBM511484(US11059789, Example 33 | US11691950, Example 33)copy SMILES
Affinity DataIC50: 81nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD72M2US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))TBA
LigandPNGBDBM511484(US11059789, Example 33 | US11691950, Example 33)copy SMILES
Affinity DataIC50: 5.00E+4nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD72M2US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))TBA
LigandPNGBDBM511484(US11059789, Example 33 | US11691950, Example 33)copy SMILES
Affinity DataIC50: 4.24E+4nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD72M2US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))TBA
LigandPNGBDBM511484(US11059789, Example 33 | US11691950, Example 33)copy SMILES
Affinity DataIC50: 3.01E+4nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD72M2US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))TBA
LigandPNGBDBM511484(US11059789, Example 33 | US11691950, Example 33)copy SMILES
Affinity DataIC50: 5.00E+4nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD72M2US Patent
LigandPNGBDBM511484(US11059789, Example 33 | US11691950, Example 33)copy SMILES
Affinity DataIC50: 4.01E+4nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD72M2US Patent
TargetProtein kinase C alpha type(Homo sapiens (Human))TBA
LigandPNGBDBM511484(US11059789, Example 33 | US11691950, Example 33)copy SMILES
Affinity DataIC50: 145nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD72M2US Patent
TargetProtein kinase C delta type(Homo sapiens (Human))TBA
LigandPNGBDBM511484(US11059789, Example 33 | US11691950, Example 33)copy SMILES
Affinity DataIC50: 142nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD72M2US Patent
TargetProtein kinase C epsilon type(Homo sapiens (Human))TBA
LigandPNGBDBM511484(US11059789, Example 33 | US11691950, Example 33)copy SMILES
Affinity DataIC50: 1.58E+3nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD72M2US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM511484(US11059789, Example 33 | US11691950, Example 33)copy SMILES
Affinity DataIC50: 21nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9