null

SMILES C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)COC(=O)C1CC1C(=O)OCc1ccc(cc1)[C@@H](CN)C(=O)Nc1ccc2cnccc2c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 27 hits for monomerid = 511485   

TargetRho-associated protein kinase 2(Homo sapiens (Human))TBA
LigandPNGBDBM511485(US11059789, Example 27 | US11691950, Example 27)copy SMILES
Affinity DataIC50: 13nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))TBA
LigandPNGBDBM511485(US11059789, Example 27 | US11691950, Example 27)copy SMILES
Affinity DataIC50: 2.64E+3nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD72M2US Patent
LigandPNGBDBM511485(US11059789, Example 27 | US11691950, Example 27)copy SMILES
Affinity DataIC50: 317nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))TBA
LigandPNGBDBM511485(US11059789, Example 27 | US11691950, Example 27)copy SMILES
Affinity DataIC50: 5.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))TBA
LigandPNGBDBM511485(US11059789, Example 27 | US11691950, Example 27)copy SMILES
Affinity DataIC50: 4.17E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))TBA
LigandPNGBDBM511485(US11059789, Example 27 | US11691950, Example 27)copy SMILES
Affinity DataIC50: 1.16E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))TBA
LigandPNGBDBM511485(US11059789, Example 27 | US11691950, Example 27)copy SMILES
Affinity DataIC50: 5.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9
LigandPNGBDBM511485(US11059789, Example 27 | US11691950, Example 27)copy SMILES
Affinity DataIC50: 4.68E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9
TargetProtein kinase C eta type(Homo sapiens (Human))TBA
LigandPNGBDBM511485(US11059789, Example 27 | US11691950, Example 27)copy SMILES
Affinity DataIC50: 331nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9
TargetProtein kinase C delta type(Homo sapiens (Human))TBA
LigandPNGBDBM511485(US11059789, Example 27 | US11691950, Example 27)copy SMILES
Affinity DataIC50: 509nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9
TargetProtein kinase C epsilon type(Homo sapiens (Human))TBA
LigandPNGBDBM511485(US11059789, Example 27 | US11691950, Example 27)copy SMILES
Affinity DataIC50: 3.46E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))TBA
LigandPNGBDBM511485(US11059789, Example 27 | US11691950, Example 27)copy SMILES
Affinity DataIC50: 2.64E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))TBA
LigandPNGBDBM511485(US11059789, Example 27 | US11691950, Example 27)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9
LigandPNGBDBM511485(US11059789, Example 27 | US11691950, Example 27)copy SMILES
Affinity DataIC50: 1.00E+5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))TBA
LigandPNGBDBM511485(US11059789, Example 27 | US11691950, Example 27)copy SMILES
Affinity DataIC50: 1.79E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9
TargetRho-associated protein kinase 2(Homo sapiens (Human))TBA
LigandPNGBDBM511485(US11059789, Example 27 | US11691950, Example 27)copy SMILES
Affinity DataIC50: 13nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD72M2US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM511485(US11059789, Example 27 | US11691950, Example 27)copy SMILES
Affinity DataIC50: 29nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD72M2US Patent
LigandPNGBDBM511485(US11059789, Example 27 | US11691950, Example 27)copy SMILES
Affinity DataIC50: 317nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD72M2US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))TBA
LigandPNGBDBM511485(US11059789, Example 27 | US11691950, Example 27)copy SMILES
Affinity DataIC50: 5.00E+4nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD72M2US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))TBA
LigandPNGBDBM511485(US11059789, Example 27 | US11691950, Example 27)copy SMILES
Affinity DataIC50: 4.17E+4nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD72M2US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))TBA
LigandPNGBDBM511485(US11059789, Example 27 | US11691950, Example 27)copy SMILES
Affinity DataIC50: 1.16E+4nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD72M2US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))TBA
LigandPNGBDBM511485(US11059789, Example 27 | US11691950, Example 27)copy SMILES
Affinity DataIC50: 5.00E+4nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD72M2US Patent
LigandPNGBDBM511485(US11059789, Example 27 | US11691950, Example 27)copy SMILES
Affinity DataIC50: 4.68E+4nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD72M2US Patent
TargetProtein kinase C alpha type(Homo sapiens (Human))TBA
LigandPNGBDBM511485(US11059789, Example 27 | US11691950, Example 27)copy SMILES
Affinity DataIC50: 331nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD72M2US Patent
TargetProtein kinase C delta type(Homo sapiens (Human))TBA
LigandPNGBDBM511485(US11059789, Example 27 | US11691950, Example 27)copy SMILES
Affinity DataIC50: 509nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD72M2US Patent
TargetProtein kinase C epsilon type(Homo sapiens (Human))TBA
LigandPNGBDBM511485(US11059789, Example 27 | US11691950, Example 27)copy SMILES
Affinity DataIC50: 3.46E+3nMAssay Description:The TNFα assay quantifies secreted TNFα from RAW264.7 immortalized murine macrophages as an indicator of inflammation. The cells were concu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD72M2US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM511485(US11059789, Example 27 | US11691950, Example 27)copy SMILES
Affinity DataIC50: 29nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9