null

SMILES CC1(C)Cc2cc(ccc2N1)C1=C(c2ccc(O[C@H]3CCN(CCCF)C3)nc2)c2ccc(O)cc2CCC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 521418   

TargetEstrogen receptor [298-554](Homo sapiens (Human))TBA
LigandPNGBDBM521418(6-(2,2- dimethylindolin- 5-yl)-5-[6-[(3S)- 1-(3- f...)copy SMILES
Affinity DataIC50: 1nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NZ8BT3US Patent
TargetEstrogen receptor [298-554,Y537S](Homo sapiens (Human))TBA
LigandPNGBDBM521418(6-(2,2- dimethylindolin- 5-yl)-5-[6-[(3S)- 1-(3- f...)copy SMILES
Affinity DataIC50: 7nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NZ8BT3US Patent
TargetEstrogen receptor [298-554,D538G](Homo sapiens (Human))TBA
LigandPNGBDBM521418(6-(2,2- dimethylindolin- 5-yl)-5-[6-[(3S)- 1-(3- f...)copy SMILES
Affinity DataIC50: 9nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreenŽ TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NZ8BT3US Patent