null

SMILES CC(C)N1CCOc2c(Cl)cc(cc12)-c1nc(Nc2ccc(N3CCNCC3)c(F)c2)ncc1Cl

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 525746   

TargetCyclin-dependent kinase 4(Homo sapiens (Human))TBA
LigandPNGBDBM525746(US11174252, Compound 52)copy SMILES
Affinity DataIC50: 89nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27D2Z99US Patent
LigandPNGBDBM525746(US11174252, Compound 52)copy SMILES
Affinity DataIC50: 14nMAssay Description:FMS: IC50 values of compounds against FMS kinase were determined by LanthaScreen™ Eu Kinase Binding Assay at Invitrogen (Life Technologies Grand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27D2Z99US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))TBA
LigandPNGBDBM525746(US11174252, Compound 52)copy SMILES
Affinity DataIC50: 200nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27D2Z99US Patent