null

SMILES CC(C)N1CCOc2c(F)cc(cc12)-c1nc(Nc2ccc(cn2)C2CCN(C)C2)ncc1F

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 525806   

TargetCyclin-dependent kinase 4(Homo sapiens (Human))TBA
LigandPNGBDBM525806(US11174252, Compound 498)copy SMILES
Affinity DataIC50: 1nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27D2Z99US Patent
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))TBA
LigandPNGBDBM525806(US11174252, Compound 498)copy SMILES
Affinity DataIC50: 155nMAssay Description:CDK5 (p25): IC50 values of compounds against CDK5 (p25) were determined by Z′-LYTE™. These screening assays were performed at Invitrogen L...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27D2Z99US Patent
LigandPNGBDBM525806(US11174252, Compound 498)copy SMILES
Affinity DataIC50: 223nMAssay Description:CDK1 (cyclin B): IC50 values of compounds against CDK1 (cyclin B) were determined by Z′-LYTE™. These screening assays were performed at In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27D2Z99US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))TBA
LigandPNGBDBM525806(US11174252, Compound 498)copy SMILES
Affinity DataIC50: 3nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27D2Z99US Patent