null
SMILES c1nn2cc(cnc2c1-c1ccncc1)-c1ccncc1
InChI Key InChIKey=ZLISHOMLHVNDJG-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 5417
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University of KwaZulu-Natal
Curated by ChEMBL
University of KwaZulu-Natal
Curated by ChEMBL
Affinity DataIC50: 224nMAssay Description:Inhibition of recombinant human GST-fused KDR kinase expressed in insect Sf21 cells using poly-Glu/Tyr (4:1) peptide as substrateMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University of KwaZulu-Natal
Curated by ChEMBL
University of KwaZulu-Natal
Curated by ChEMBL
Affinity DataIC50: 224nMpH: 7.4 T: 2°CAssay Description:Activated KDR was incubated with 25 uM/10 uCi of [gamma-33P] ATP, poly-Glu/Tyr, and inhibitors in kinase buffer for 15 min at 22 °C. The reactio...More data for this Ligand-Target Pair