null

SMILES CN1CCN(CC1)c1ccc(Nc2ncc3ccn(-c4ccc(F)c(NS(=O)(=O)C(C)(C)C)c4)c3n2)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 543629   

TargetBromodomain-containing protein 4 [75-147](Homo sapiens (Human))TBA
LigandPNGBDBM543629(US11279703, TABLE 6.218 | US11279703, TABLE 6.263)copy SMILES
Affinity DataIC50: 128nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43X8BUS Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))TBA
LigandPNGBDBM543629(US11279703, TABLE 6.218 | US11279703, TABLE 6.263)copy SMILES
Affinity DataIC50: 35nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43X8BUS Patent
TargetBromodomain-containing protein 4 [342-460](Homo sapiens (Human))TBA
LigandPNGBDBM543629(US11279703, TABLE 6.218 | US11279703, TABLE 6.263)copy SMILES
Affinity DataIC50: 67.5nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43X8BUS Patent
TargetBromodomain-containing protein 2 [91-163](Homo sapiens (Human))TBA
LigandPNGBDBM543629(US11279703, TABLE 6.218 | US11279703, TABLE 6.263)copy SMILES
Affinity DataIC50: 490nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43X8BUS Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))TBA
LigandPNGBDBM543629(US11279703, TABLE 6.218 | US11279703, TABLE 6.263)copy SMILES
Affinity DataIC50: 188nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43X8BUS Patent
TargetBromodomain testis-specific protein [22-138](Homo sapiens (Human))TBA
LigandPNGBDBM543629(US11279703, TABLE 6.218 | US11279703, TABLE 6.263)copy SMILES
Affinity DataIC50: 182nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43X8BUS Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))TBA
LigandPNGBDBM543629(US11279703, TABLE 6.218 | US11279703, TABLE 6.263)copy SMILES
Affinity DataIC50: 972nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43X8BUS Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))TBA
LigandPNGBDBM543629(US11279703, TABLE 6.218 | US11279703, TABLE 6.263)copy SMILES
Affinity DataIC50: 105nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43X8BUS Patent
TargetBromodomain-containing protein 4 [75-147](Homo sapiens (Human))TBA
LigandPNGBDBM543629(US11279703, TABLE 6.218 | US11279703, TABLE 6.263)copy SMILES
Affinity DataIC50: 228nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43X8BUS Patent
TargetBromodomain-containing protein 3 [51-123](Homo sapiens (Human))TBA
LigandPNGBDBM543629(US11279703, TABLE 6.218 | US11279703, TABLE 6.263)copy SMILES
Affinity DataIC50: 109nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43X8BUS Patent