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SMILES CC(C)(C)S(=O)(=O)Nc1cccc(c1)-c1csc2cnc(Nc3ccc4C5CNCCN5CCc4c3)nc12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 543797   

TargetBromodomain-containing protein 4 [75-147](Homo sapiens (Human))TBA
LigandPNGBDBM543797(US11279703, TABLE 6.387)copy SMILES
Affinity DataIC50: 109nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43X8BUS Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))TBA
LigandPNGBDBM543797(US11279703, TABLE 6.387)copy SMILES
Affinity DataIC50: 2nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43X8BUS Patent
TargetBromodomain-containing protein 4 [342-460](Homo sapiens (Human))TBA
LigandPNGBDBM543797(US11279703, TABLE 6.387)copy SMILES
Affinity DataIC50: 131nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43X8BUS Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))TBA
LigandPNGBDBM543797(US11279703, TABLE 6.387)copy SMILES
Affinity DataIC50: 18nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43X8BUS Patent
TargetBromodomain-containing protein 3 [51-123](Homo sapiens (Human))TBA
LigandPNGBDBM543797(US11279703, TABLE 6.387)copy SMILES
Affinity DataIC50: 100nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43X8BUS Patent
TargetBromodomain testis-specific protein [22-138](Homo sapiens (Human))TBA
LigandPNGBDBM543797(US11279703, TABLE 6.387)copy SMILES
Affinity DataIC50: 281nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43X8BUS Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))TBA
LigandPNGBDBM543797(US11279703, TABLE 6.387)copy SMILES
Affinity DataIC50: 44nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43X8BUS Patent
TargetBromodomain-containing protein 2 [91-163](Homo sapiens (Human))TBA
LigandPNGBDBM543797(US11279703, TABLE 6.387)copy SMILES
Affinity DataIC50: 489nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43X8BUS Patent