null

SMILES CC1(C)CCC(CN2CCN(CC2)c2ccc(cc2)C(=O)NS(=O)(=O)c2ccc(N[C@H](CCN3CCNCC3)CSc3ccccc3)c(c2)S(=O)(=O)C(F)(F)F)=C(C1)C12CC(C1)(C2)C(F)F

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 552944   

TargetBcl-2-like protein 1(Homo sapiens (Human))TBA
LigandPNGBDBM552944((R)-4-(4-((2-(3-(difluoromethyl)bicyclo[1.1.1]pent...)copy SMILES
Affinity DataIC50: 10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HD7ZW9US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))TBA
LigandPNGBDBM552944((R)-4-(4-((2-(3-(difluoromethyl)bicyclo[1.1.1]pent...)copy SMILES
Affinity DataIC50: 10nMAssay Description:Table 2: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was also assessed using an HTRF assay. Background: FAM-Bak/Bad binds to surface pocket of the Bc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HD7ZW9US Patent