null

SMILES COc1cc(cc(OC)c1CN(C)CC12CC(C1)(C2)C(=O)NCCOCCOCCNc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12)-c1cn(C)c(=O)c2cnccc12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 565296   

LigandPNGBDBM565296(3-[([[2,6-dimethoxy-4-(2-methyl-1-oxo-2,7-naphthyr...)copy SMILES
Affinity DataIC50: 550nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6H41US Patent
TargetBromodomain-containing protein 9 [133-239](Homo sapiens (Human))TBA
LigandPNGBDBM565296(3-[([[2,6-dimethoxy-4-(2-methyl-1-oxo-2,7-naphthyr...)copy SMILES
Affinity DataIC50: 10nMAssay Description:A mixture of biotinylated-ligand and SureLight Allophycocyanin-Streptavidin (APC-SA, PerkinElmer AD0201) in 50 mM HEPES (pH 7.4), 50 mM NaCl, 1 mM TC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2571G8BUS Patent
TargetBromodomain-containing protein 9 [133-239](Homo sapiens (Human))TBA
LigandPNGBDBM565296(3-[([[2,6-dimethoxy-4-(2-methyl-1-oxo-2,7-naphthyr...)copy SMILES
Affinity DataIC50: 55nMAssay Description:Procedure: His-Flag-BRD9 (P133-K239; Swiss Prot Q9H8M2; SEQ ID NO:1 mgsshhhhhhenlyfq/gdykddddkgslevlfqg/PAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMII...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6H41US Patent