null

SMILES Cc1cccc(n1)C(=O)N1CC\C(=C/C#Cc2cccc(Cl)c2)C(C)(C)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 571428   

TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))TBA
LigandPNGBDBM571428(US11440922, Example 128 | {(4E)-4-[3-(3- chlorophe...)copy SMILES
Affinity DataKi:  1.82nMAssay Description:Affinity at transmembrane glutamate metabotropic cloned human mGluR5 receptor was evaluated according to the methods of Anderson (Anderson et al., J ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9NGPUS Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))TBA
LigandPNGBDBM571428(US11440922, Example 128 | {(4E)-4-[3-(3- chlorophe...)copy SMILES
Affinity DataEC50:  165nMAssay Description:The PAM potency was evaluated by performing an agonist concentration response curve in the presence of the compounds. The compounds at fixed concentr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9NGPUS Patent