null

SMILES Cc1cc(C(=O)N2CC\C(=C/C#Cc3cc(F)cc(c3)C#N)C(C)(C)C2)c(C)o1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 571432   

TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))TBA
LigandPNGBDBM571432(3-[(3E)-3-{1-[(2,5- dimethylfuran-3- yl)carbonyl]-...)copy SMILES
Affinity DataKi:  637nMAssay Description:Affinity at transmembrane glutamate metabotropic cloned human mGluR5 receptor was evaluated according to the methods of Anderson (Anderson et al., J ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9NGPUS Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))TBA
LigandPNGBDBM571432(3-[(3E)-3-{1-[(2,5- dimethylfuran-3- yl)carbonyl]-...)copy SMILES
Affinity DataEC50:  291nMAssay Description:The PAM potency was evaluated by performing an agonist concentration response curve in the presence of the compounds. The compounds at fixed concentr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9NGPUS Patent