null
SMILES NCCCC[C@@H]1NC(=O)CCSCc2cccc(CSC[C@H](NC(=O)[C@@H]3C[C@@H](CN3C(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@H](Cc3cncn3)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc3cnc4ccc(F)cc34)NC(=O)[C@H](Cc3cnc4ccc(F)cc34)NC(=O)CNC1=O)C(F)(F)F)C(N)=O)c2
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 586225
TargetProprotein convertase subtilisin/kexin type 9/Low-density lipoprotein receptor(Homo sapiens (Human))TBA
Affinity DataIC50: 50nMAssay Description:A set of cyclic polypeptides were identified to inhibit the interaction between human PCSK9 and human LDLR. Each polypeptide has an N-terminal amino ...More data for this Ligand-Target Pair
TargetProprotein convertase subtilisin/kexin type 9/Low-density lipoprotein receptor(Homo sapiens (Human))TBA
Affinity DataIC50: 50nMAssay Description:The PCSK9 Alexa FRET Plus assay measured the interaction between PCSK9 and an AlexaFluor647 (AF) tagged cyclic peptide, Reagent B (KD=35 nM). A solut...More data for this Ligand-Target Pair
TargetProprotein convertase subtilisin/kexin type 9/Low-density lipoprotein receptor(Homo sapiens (Human))TBA
Affinity DataIC50: 50nMAssay Description:The PCSK9 Alexa FRET Standard assay measured the interaction between PCSK9 and an AlexaFluor647 (AF) tagged cyclic peptide, Reagent A (KD=83 nM). A s...More data for this Ligand-Target Pair