null

SMILES Clc1cccc(Nc2ncc(cn2)-c2cncc(N[C@H]3CCN(C3)C(=O)C=C)c2)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 588142   

TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM588142(1-[3-[[5-[2-(3- chloroanilino) pyrimidin-5-yl]-3-...)copy SMILES
Affinity DataIC50: 1.37E+3nMAssay Description:The BTK and EGFR biochemical assays utilize LANTHASCREENŽ Eu Kinase Binding Assays from Thermo Fisher Scientific, measuring the binding of the kinase...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38XD6US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))TBA
LigandPNGBDBM588142(1-[3-[[5-[2-(3- chloroanilino) pyrimidin-5-yl]-3-...)copy SMILES
Affinity DataIC50: 6.01nMAssay Description:The BTK and EGFR biochemical assays utilize LANTHASCREENŽ Eu Kinase Binding Assays from Thermo Fisher Scientific, measuring the binding of the kinase...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38XD6US Patent