null

SMILES COc1ccc(Cc2nc3n(nc(C(C)C)c3c(=O)[nH]2)-c2c(Cl)cccc2Cl)cc1

InChI Key InChIKey=CCJDCSCSJGFHNH-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 59229   

TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
GPC Biotech, Inc.

LigandPNGBDBM59229(Pyrazolopyrimidone analog, RGB-286331)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Inhibition of in vitro kinase activity of purified CDKs.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3BR6PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
GPC Biotech, Inc.

LigandPNGBDBM59229(Pyrazolopyrimidone analog, RGB-286331)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibition of HCT116 cell proliferation after 72hr of incubation with compounds was determined by SRB Assay.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3BR6PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
GPC Biotech, Inc.

LigandPNGBDBM59229(Pyrazolopyrimidone analog, RGB-286331)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of in vitro kinase activity of purified CDKs.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3BR6PubMed