null

SMILES CC[C@@H]1CN([C@@H](CC)CN1C(c1noc(n1)C1CC1)c1ccc(F)cc1)c1nc(=O)n(C)c2ccc(nc12)C#N

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 594558   

LigandPNGBDBM594558(US11584747, Example 371 | US11584747, Example 372)copy SMILES
Affinity DataIC50: 13nMAssay Description:The reactions were carried out in 50 mM MOPS pH 7.5, 100 mM NaCl, 10 mM MgCl2, 1 μM CaCl2, and 1 mM DTT (assay buffer). The reactions using a de...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z89HB5US Patent
TargetDiacylglycerol kinase zeta(Homo sapiens)TBA
LigandPNGBDBM594558(US11584747, Example 371 | US11584747, Example 372)copy SMILES
Affinity DataIC50: 43nMAssay Description:The reactions were carried out in 50 mM MOPS pH 7.5, 100 mM NaCl, 10 mM MgCl2, 1 μM CaCl2, and 1 mM DTT (assay buffer). The reactions using a de...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z89HB5US Patent
LigandPNGBDBM594558(US11584747, Example 371 | US11584747, Example 372)copy SMILES
Affinity DataIC50: 4nMAssay Description:The reactions were carried out in 50 mM MOPS pH 7.5, 100 mM NaCl, 10 mM MgCl2, 1 μM CaCl2, and 1 mM DTT (assay buffer). The reactions using a de...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z89HB5US Patent
TargetDiacylglycerol kinase zeta(Homo sapiens)TBA
LigandPNGBDBM594558(US11584747, Example 371 | US11584747, Example 372)copy SMILES
Affinity DataIC50: 100nMAssay Description:The reactions were carried out in 50 mM MOPS pH 7.5, 100 mM NaCl, 10 mM MgCl2, 1 μM CaCl2, and 1 mM DTT (assay buffer). The reactions using a de...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z89HB5US Patent