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SMILES COc1cc(\C=C\C(=O)CC(=O)\C=C\c2ccc(cc2)N(C)C)ccc1O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 597754   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))TBA
LigandPNGBDBM597754(US11608309, Compound 4)copy SMILES
Affinity DataIC50: 1.70E+4nMAssay Description:Table 1 shows the IC50 of curcumin, compound 1, and compound 2, compared to a standard Zn++ binding & MMPI (matrix metalloproteinase inhibitor), 1,10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47T2HUS Patent
TargetCollagenase 3 (MMP13)(Homo sapiens (Human))TBA
LigandPNGBDBM597754(US11608309, Compound 4)copy SMILES
Affinity DataIC50: 2.50E+5nMAssay Description:Table 10: The efficacy of MMP-2 inhibition was as follows: compound 6>compound 7>compound 8. Although compound 6 showed similar efficacy as curcumin ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47T2HUS Patent
Target72 kDa type IV collagenase (MMP2)(Homo sapiens (Human))TBA
LigandPNGBDBM597754(US11608309, Compound 4)copy SMILES
Affinity DataIC50: 2.50E+5nMAssay Description:Table 10: The efficacy of MMP-2 inhibition was as follows: compound 6>compound 7>compound 8. Although compound 6 showed similar efficacy as curcumin ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47T2HUS Patent