null

SMILES CC1C(=O)Nc2cc3cnc(Nc4ccc(cc4)S(N)(=O)=O)nc3n2C11CCCCC1

InChI Key

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 601942   

TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))TBA

LigandBDBM601942(4-((8'-methyl-7'-oxo-7',8'-dihydro- 6'H-spiro[cycl...)copy SMILES

Affinity DataIC50: 1nMMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0MGD

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))TBA

LigandBDBM601942(4-((8'-methyl-7'-oxo-7',8'-dihydro- 6'H-spiro[cycl...)copy SMILES

Affinity DataIC50: 1nMMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0MGD

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))TBA

LigandBDBM601942(4-((8'-methyl-7'-oxo-7',8'-dihydro- 6'H-spiro[cycl...)copy SMILES

Affinity DataIC50: 57nMMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0MGD

TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Homo sapiens (Human))TBA

LigandBDBM601942(4-((8'-methyl-7'-oxo-7',8'-dihydro- 6'H-spiro[cycl...)copy SMILES

Affinity DataIC50: 147nMMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0MGD

TargetCyclin-dependent kinase 7(Homo sapiens (Human))TBA

LigandBDBM601942(4-((8'-methyl-7'-oxo-7',8'-dihydro- 6'H-spiro[cycl...)copy SMILES

Affinity DataIC50: 83nMMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0MGD

TargetCyclin-dependent kinase 1(Homo sapiens (Human))TBA

LigandBDBM601942(4-((8'-methyl-7'-oxo-7',8'-dihydro- 6'H-spiro[cycl...)copy SMILES

Affinity DataIC50: 7nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0MGD

TargetCyclin-dependent kinase 3/G1/S-specific cyclin-E1(Homo sapiens (Human))TBA

LigandBDBM601942(4-((8'-methyl-7'-oxo-7',8'-dihydro- 6'H-spiro[cycl...)copy SMILES

Affinity DataIC50: 10nMMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0MGD

TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))TBA

LigandBDBM601942(4-((8'-methyl-7'-oxo-7',8'-dihydro- 6'H-spiro[cycl...)copy SMILES

Affinity DataIC50: 2nMMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0MGD

TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))TBA

LigandBDBM601942(4-((8'-methyl-7'-oxo-7',8'-dihydro- 6'H-spiro[cycl...)copy SMILES

Affinity DataIC50: 6nMMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0MGD