null

SMILES COc1cc(OC)cc(c1)-c1cc2cnc(NCCCCN3CCOCC3)cc2nc1NC(=O)NC(C)(C)C

InChI Key InChIKey=YEIRROBVFZDCIW-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 6150   

TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
University of Auckland

LigandPNGBDBM6150(1,6-naphthyridine 19 | 3-tert-butyl-1-[3-(3,5-dime...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+4nMAssay Description:Compounds were evaluated for their ability to prevent phosphorylation of a model glutamate-tyrosine copolymer substrate by isolated human FGFR-1, mou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6150(1,6-naphthyridine 19 | 3-tert-butyl-1-[3-(3,5-dime...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Tha assay was using human VEGFR-2 in DELFIA (dissociation-enhanced lanthanide fluoroimmunoassay) format. IC50 is the concentration of inhibitor that ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6150(1,6-naphthyridine 19 | 3-tert-butyl-1-[3-(3,5-dime...)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+4nMAssay Description:Compounds were evaluated for their ability to prevent phosphorylation of a model glutamate-tyrosine copolymer substrate by isolated human FGFR-1, mou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM6150(1,6-naphthyridine 19 | 3-tert-butyl-1-[3-(3,5-dime...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Compounds were evaluated for their ability to prevent phosphorylation of a model glutamate-tyrosine copolymer substrate by isolated human FGFR-1, mou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H3WPubMed