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SMILES CN(C)CCCN1c2ccccc2Sc2ccc(cc12)C(F)(F)F

InChI Key InChIKey=XSCGXQMFQXDFCW-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 67544   

TargetD(2) dopamine receptor(BOVINE)
TBA

Curated by PDSP Ki Database
LigandPNGBDBM67544(N,N-dimethyl-3-[2-(trifluoromethyl)-10-phenothiazi...)copy SMILEScopy InChI
Affinity DataKi:  2.10nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B8WH6PubMed
TargetD(2) dopamine receptor(BOVINE)
TBA

Curated by PDSP Ki Database
LigandPNGBDBM67544(N,N-dimethyl-3-[2-(trifluoromethyl)-10-phenothiazi...)copy SMILEScopy InChI
Affinity DataKi:  2.10nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27S7M9VPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Mayo Clinic and Foundation

Curated by PDSP Ki Database
LigandPNGBDBM67544(N,N-dimethyl-3-[2-(trifluoromethyl)-10-phenothiazi...)copy SMILEScopy InChI
Affinity DataKi:  2.80nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7G5BPubMedDrugBank
TargetHistamine H1 receptor(RAT)
TBA

Curated by PDSP Ki Database
LigandPNGBDBM67544(N,N-dimethyl-3-[2-(trifluoromethyl)-10-phenothiazi...)copy SMILEScopy InChI
Affinity DataKi:  52nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN14P6PubMed
TargetD(1A) dopamine receptor(BOVINE)
TBA

Curated by PDSP Ki Database
LigandPNGBDBM67544(N,N-dimethyl-3-[2-(trifluoromethyl)-10-phenothiazi...)copy SMILEScopy InChI
Affinity DataKi:  530nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27S7M9VPubMed
TargetD(1A) dopamine receptor(BOVINE)
TBA

Curated by PDSP Ki Database
LigandPNGBDBM67544(N,N-dimethyl-3-[2-(trifluoromethyl)-10-phenothiazi...)copy SMILEScopy InChI
Affinity DataKi:  530nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B8WH6PubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
TBA

Curated by PDSP Ki Database
LigandPNGBDBM67544(N,N-dimethyl-3-[2-(trifluoromethyl)-10-phenothiazi...)copy SMILEScopy InChI
Affinity DataKi:  605nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9NXWPubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Bulgarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM67544(N,N-dimethyl-3-[2-(trifluoromethyl)-10-phenothiazi...)copy SMILEScopy InChI
Affinity DataKi:  1.57E+4nMAssay Description:Concentration giving half of the maximal ATPase activity calculated for the high-affinity binding site of the CHO P-Glycoprotein (P-gp) in two-affini...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23B60VGPubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM67544(N,N-dimethyl-3-[2-(trifluoromethyl)-10-phenothiazi...)copy SMILEScopy InChI
Affinity DataKi:  3.02E+4nMAssay Description:Inhibitory activity against recombinant Trypanosoma cruzi (T. cruzi) Trypanothione reductase (linear competitive type)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP457XPubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
University of Bonn

LigandPNGBDBM67544(N,N-dimethyl-3-[2-(trifluoromethyl)-10-phenothiazi...)copy SMILEScopy InChI
Affinity DataEC50:  6.39E+3nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9ST6PubMed
TargetOrf1a protein(MERS-CoV)
University of Bonn

LigandPNGBDBM67544(N,N-dimethyl-3-[2-(trifluoromethyl)-10-phenothiazi...)copy SMILEScopy InChI
Affinity DataEC50:  5.75E+3nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9ST6PubMed
TargetBile salt export pump(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM67544(N,N-dimethyl-3-[2-(trifluoromethyl)-10-phenothiazi...)copy SMILEScopy InChI
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 3 receptor in rat cortical membranes using [3H]- 1-Methyl-1H-indazole-3-carboxylic acid (8-methyl-8-a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP488MPubMed
TargetPleiotropic ABC efflux transporter of multiple drugs(Saccharomyces cerevisiae S288c)
Wroclaw Medical University

Curated by ChEMBL
LigandPNGBDBM67544(N,N-dimethyl-3-[2-(trifluoromethyl)-10-phenothiazi...)copy SMILEScopy InChI
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of Pdr5p-mediated rhodamine 6G transport in Saccharomyces cerevisiae MKPDR5h plasma membrane by spectrofluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125TNZPubMed
TargetCholinesterase(Equus caballus (Horse))
Universit£ degli Studi di Genova

Curated by ChEMBL
LigandPNGBDBM67544(N,N-dimethyl-3-[2-(trifluoromethyl)-10-phenothiazi...)copy SMILEScopy InChI
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of Equine serum BChE using butyrylthiocoline iodide as a substrate after 20 mins by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CPGPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM67544(N,N-dimethyl-3-[2-(trifluoromethyl)-10-phenothiazi...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails
TargetNADPH oxidase 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM67544(N,N-dimethyl-3-[2-(trifluoromethyl)-10-phenothiazi...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+4nMAssay Description:Data Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institut...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KK998GPCBioAssay
TargetProteasome subunit alpha type-6(Homo sapiens (Human))
Michigan State University

LigandPNGBDBM67544(N,N-dimethyl-3-[2-(trifluoromethyl)-10-phenothiazi...)copy SMILEScopy InChI
Affinity DataEC50:  7.80E+3nMpH: 7.5 T: 2°CAssay Description:Activity assays were carried out in a 200 uL reaction volume. Different concentrations of test compounds were added to a black flat/clear bottom 96-w...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1H2FPubMed